Primary Care provides the best opportunity to identify and respond to risk factors for chronic disease. For most residents in Queensland general practice is the most accessible health service and best placed to screen, manage and coordinate care with other disciplines for patients with chronic disease. General Practice responds to approximately 80-85% of the population in any given year and has the ability to respond to any chronic disease in all populations. Primary Care has undergone and is undergoing significant reforms to technologies, funding models and practice models (corporatisation) with little systematic research, thus creating a rich research environment for BDHP collaborations. The BDHP Chronic Disease Theme will connect with primary care researchers, industry leaders and clinicians to create the best multidisciplinary environments to prevent, screen, and manage chronic disease.